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Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volumeNARA Subscribed
The concept of age acceleration, the difference between biological age and chronological age, is of growing interest, particularly with respect to age-related disorders, such as Alzheimer’s Disease (AD). Whilst studies have reported associations with AD risk and related phenotypes, there remains a lack of consensus on these associations. Here we aimed to comprehensively investigate the relationship between five recognised meas...
Biogeographic mechanisms involved in the colonization of Madagascar by African vertebrates: Rifting, rafting and runwaysNARA Subscribed
Aim For 80 years, popular opinion has held that most of Madagascar's terrestrial vertebrates arrived from Africa by transoceanic dispersal (i.e. rafting or swimming). We reviewed this proposition, focussing on three ad hoc hypotheses proposed to render this unlikely scenario more feasible: (a) Could hibernation have helped mammals to reach Madagascar? (b) Could the aquatic abilities of hippopotamuses have enabled them to swim...
Aim Small body size in Madagascar's dwarf and mouse lemurs (Cheirogaleidae) is generally viewed as primitive. We investigated the evolution of body size in this family and in its sister‐taxon, the Lepilemuridae, from phylogenetic, ontogenetic and adaptive perspectives. Location Madagascar. Methods We used a phylogenetic method to reconstruct the evolution of body size in lemurs, and allometric regression models of gestation pe...
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