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Background and aim Soil nutrient availability, acidification associated with plant phosphorus-mining strategies, and fine root foraging all influence nutrient cycling. However, their relative impacts on microbial nutrient cycling during primary succession remain unclear. Methods We studied a 130-year primary succession along the Hailuogou post-glacial chronosequence in southwest China. Early-successional stages (1–3) are domin...
Introduction Driven by global climate change and coastal eutrophication, severe hypoxic events have become a primary environmental stressor in marine ecosystems, posing a critical threat to commercially vital teleosts like the golden pompano ( Trachinotus blochii ). Understanding the dimorphic physiological and microbial responses between sexes under such stress is crucial for developing targeted mitigation strategies. Methods...
Androgen induces 3′UTR shortening of de novo lipogenesis genes by alternative polyadenylation in prostate cancer cellsNARA Subscribed
Alternative polyadenylation (APA) is a pervasive mechanism that is emerging as a formidable player in post-transcriptional regulation. The transcriptional landscape can be altered via APA in response to various stimulating factors. Using the PacBio single-molecule long-read sequencing method, we present for the first time the 3′UTR landscape and reveal a global increase of APA events in prostate cancer (PCa) LNCaP cells in res...