Eight new resin glycosides, named calyhedins XXIV ( 1 )–XXXI ( 8 ), were isolated from the rhizomes of Calystegia hederacea Wall. (Convolvulaceae), along with six known calyhedins: calyhedins II ( 9 ), III ( 10 ), IV ( 11 ), V ( 12 ), VIII ( 13 ), and XII ( 14 ). Their structures were determined from the spectroscopic data. Compounds 1 – 7 were hexa- or hepta-glycosides with macrolactone structures (jalapins), and their sugar...

Resin glycosides, characteristic of plants of the Convolvulaceae family, are well-known purgative constituents found in traditional medicinal crude drugs, such as Rhizoma Jalapae, Rhizoma Jalapae Braziliensis, Orizaba Jalapa Tuber, and Pharbitidis Semen. The isolated compounds exhibited a wide range of biological activities, including antibacterial, ionophoric, anti-inflammatory, antiviral, and multidrug-resistance-modulating...

In this paper, we review our work in the last 10 years wherein we examined the sulfides in the acetone extracts of garlic ( Allium sativum ), onion ( A. cepa ), and Welsh onion ( A. fistulosum ), obtained and characterized the structures of new sulfides, three 3,4-dimethylthiolane-type sulfides from onion and Welsh onion, respectively, and four acyclic-type, nine 3,4-dimethyl- thiolane-type, four 2-methylthiolane (and thiane)-...

Over the course of our studies investigating anti-proliferative properties of compounds originating from plants against human gastric adenocarcinoma (MK-1), human uterine carcinoma (HeLa), murine melanoma (B16F10), and two human T cell lymphotropic virus type 1 (HTLV-1)-infected T-cell lines (MT-1 and MT-2), we have screened 582 extracted samples obtained from a variety of parts from 370 plants. A few extracts showed anti-prol...