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Accurate and robust localization is essential for intelligent vessels operating in complex marine and port environments. However, single-sensor localization is often affected by limited observation range, environmental occlusion, local interference, and sensor degradation. Although multi-sensor fusion can improve localization reliability, unknown cross-correlated measurement noise arising from shared disturbances, time synchro...
Ethambutol induces optic neuropathy through SDHB-mediated ferroptosis in retinal ganglion cells via Smad4 pathwayNARA Subscribed
Ethambutol (EMB)-induced optic neuropathy (EON) is a clinical concern. Ferroptosis, involving iron and toxic reactive oxygen species (ROS), causes unique cell death, but its mechanism in EON is unclear. This study aims to explore the EON mechanisms. Wistar rats were used to establish an EON model by administering EMB at 50 mg/kg daily for 8 weeks. Retinal ganglion cells (RGC-5 cells) were used for in vitro experiments. Histolo...
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