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GeroScience · 2025 · Vol. 48 · Issue 3 · Springer
End-stage renal disease (ESRD) patients frequently experience mild cognitive impairment (MCI), which significantly affects their quality of life. Although dysfunctions in cerebrospinal fluid (CSF) circulation and neurovascular coupling (NVC) have been implicated in cognitive impairment, their interrelationship remains unclear. This study aimed to investigate the association between CSF circulation dysfunction and NVC disruptio...
Metabolic Brain Disease · 2023 · Vol. 38 · Issue 8 · Springer
End-stage kidney disease and mild cognitive impairment (ESKD-MCI) affect the quality of life and long-term treatment outcomes of patients affected by these diseases. Clarifying the morphological changes from brain injuries in ESKD-MCI and their relationship with clinical features is helpful for the early identification and intervention of MCI before it progresses to irreversible dementia. This study gathered data from 23 patie...