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Untargeted Metabolomics Reveals Major Patterns of Metabolic Shifts in Potato Seed Tubers during StorageNARA Subscribed
To obtain comprehensive insight into metabolic changes in potato seed tubers during storage and to identify patterns associated with physiological ageing, we analysed tuber metabolite composition using untargeted metabolomics based on gas and liquid chromatography-mass spectrometry (GC–MS and LC–MS). During two seasons, seed tubers of four contrasting cultivars (Agria, Festien, Innovator, and Lady Claire) were produced in a si...
The recreational fishery for pollack ( Pollachius pollachius ) in the northeast Atlantic is impacted by the species' high sensitivity to barotrauma. When captured at depth and brought to the surface, gas expansion within the peritoneal cavity can cause a variety of injuries and hinder release. Via an experimental weighted cage, this study evaluated the efficacy of releasing Pollack at depth as a barotrauma mitigation strategy....
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Multichemical Exposure Assessment Using Silicone Wristbands in Central American AdolescentsNARA Subscribed
Chemical exposures are poorly characterized in Central America, where chronic kidney disease of uncertain etiology (CKDu) is a leading cause of death. Most research evaluates occupational exposures in adults, yet early-life exposures remain understudied. We used silicone wristband passive samplers to characterize exposure to over 1,500 chemicals among Nicaraguan adolescents ( n = 80) residing in CKD high-risk communities but n...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Training for Recovery: Impact of Sprint Interval Training on Recovery Dynamics and Aerobic Performance in Kickboxing AthletesNARA Subscribed
Purpose Recovery within and between rounds is crucial to combat sports performance. We sought to determine whether sprint interval training (SIT) improves recovery dynamics and aerobic performance. Methods Eleven male kickboxing athletes (26 ± 5 years; body mass index 25 ± 3 kg/m 2 ) were recruited. Participants were tested three times for VO 2peak /time to exhaustion and critical power; baseline, 3 weeks control, 3 weeks of S...
Both local and global climate phenomena shape the hydrologic regimes of watersheds. For aridland rivers in the southwestern United States, peak flows occur during two distinct periods: spring snowmelt and summer monsoons. Although discharge ( Q ) is a primary driver of variation in the production and consumption of instream organic matter, or stream metabolism, few connection have been made regarding how climate impacts ecosys...
The Gulf of Mexico’s (also recognized by the United States government as the Gulf of America; herein referred to as “the Gulf”) valuable and diverse marine, coastal, and estuarine environments sustain many habitats, species, and economically important fisheries that are vulnerable to open ocean and coastal acidification (OOCA), including shellfish, coral reefs, and other carbonate reefs and seafloor. OOCA poses an economic thr...
Management considerations for establishing a coastal acidification monitoring system from U.S. Coastal Acidification NetworksNARA Subscribed
Ocean acidification (OA), caused by the uptake of anthropogenic carbon dioxide, is a concern for ocean resource users in coastal regions where the phenomenon is compounded by variable processes. Sustained OA monitoring systems are critical for characterization of baseline ocean conditions and identification of changes and impacts to coastal ecosystems and communities. Establishing an OA monitoring network is best accomplished...
Stoichiometric acclimation of a bacterial parasite to shifts in the diet quality of a single hostNARA Subscribed
A growing body of literature suggests that the effects of host diet on populations of parasites within a host (i.e., infrapopulations) are dictated by the elemental stoichiometry of the parasite, and new data suggest that the stoichiometric composition of parasites can shift in response to a host's diet. The consequences of this shift in parasite stoichiometry for host–parasite interactions are underexplored. Here, we present...