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Per- and Polyfluoroalkyl Substances (PFAS) Enhance Cholesterol Accumulation and Dysregulate Inflammatory Responses in MacrophagesNARA Subscribed
Epidemiological studies and in vivo animal models have shown that exposure to PFAS can lead to cardiovascular toxicity and promote atherosclerosis. In this study, we explored the effects of PFOA and PFOS exposure on lipid accumulation in macrophages and analyzed critical markers of foam cell formation, which are early precursors of atherosclerotic lesions. Our results demonstrate that PFOS and PFOA enhance lipid and cholestero...
Global Change Affects Large Herbivore Forage Biomass Through Gradual Successional Shifts and Abrupt DisturbancesNARA Subscribed
Forage availability is a key factor regulating large herbivore populations. Global changes in land use and climate may affect the spatiotemporal distribution of forage across the ranges of large herbivores, especially in mountain ecosystems. We test two synergistic hypotheses for how landscape and climate changes from 2001 to 2023 have affected forb and graminoid biomass at the peak of the growing season within and across ecor...
Animals within social groups respond to costs and benefits of sociality by adjusting the proportion of time they spend in close proximity to other individuals in the group (cohesion). Variation in cohesion between individuals, in turn, shapes important group‐level processes such as subgroup formation and fission–fusion dynamics. Although critical to animal sociality, a comprehensive understanding of the factors influencing coh...
The purpose of this study was to investigate the effects of acute nitrate (NO 3 − )-rich beetroot juice ingestion on explosive and high-intensity exercise performance, oral microbiota composition, and cognitive flexibility (i.e., function), before and after maximal intermittent running exercise. Fifteen women team-sport athletes were assigned in a randomized, double-blind, crossover design to consume concentrated NO 3 – -deple...
Marine mammals are integral to global biodiversity and marine health through their roles in coastal, benthic, and pelagic ecosystems. Marine mammals face escalating threats from climate change, pollution, and human activities, which perturb their oceanic environment. The diverse biology and extreme adaptations evolved by marine mammals make them important study subjects for understanding anthropogenic pressures on marine ecosy...
Factors in homeowners’ willingness to adopt nitrogen-reducing innovative/alternative septic systemsOA Marine
When environmental mitigation requires individual adoption, engagement approaches centered on cost effectiveness and technological efficiency alone are often insufficient. Through focus groups with adopters and prospective adopters, this research identifies factors influencing homeowners’ willingness to adopt Innovative/Alternative (I/A) septic systems for nitrogen reduction. We apply concepts from technology adoption and beha...
Across the United States, development, gentrification, and water quality degradation have altered our access to the coasts, redistributing the benefits from those spaces. Building on prior coastal and green space access research, we examined different populations’ relative travel distances to all public coastal access and to public marine swimming beaches across the state of Rhode Island, by race, ethnicity, and socioeconomics...
Genetic variation and local adaptation at a cheatgrass ( Bromus tectorum ) invasion edge in western NevadaNARA Subscribed
Cheatgrass ( Bromus tectorum ) is an invasive weed in western North America found primarily growing at elevations less than 2200 m. We asked whether cheatgrass is capable of becoming adapted to a marginal habitat, by investigating a population at a high elevation invasion edge. We used a combination of methods, including reciprocal field transplants, controlled environment studies and molecular analysis. High levels of SSR gen...
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