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Fatty acid profiling is a widely used tool in cetacean dietary and health assessments, yet most studies focus exclusively on blubber, overlooking the epidermis – the largest organ and primary barrier against environmental stressors – which remains largely uncharacterised, despite its accessibility for sampling of live and deceased animals. Here, we present a comparative analysis of fatty acid composition across the epidermis a...
An unexpected assemblage: Moissanite and carbonaceous material from SSZ mantle rocks of the Dun Mountain Ophiolite, New ZealandNARA Subscribed
Moissanite (SiC) and other super-reducing minerals have been reported from supra-subduction zone (SSZ) ophiolites, yet their origin remains controversial given the oxidized conditions expected in forearc mantle. In this study, hundreds of moissanite grains have been recovered from mantle rocks of the Early Permian Dun Mountain Ophiolite, New Zealand. We report the first occurrence of moissanite found in direct association with...
Dryland ecosystems cover 41% of Earth's land surfaces, account for 44% of cultivated lands and 60% of food sources, and make large contributions to the global water and carbon cycles. However, these ecosystems are experiencing unprecedented extremes including heatwaves, floods, and droughts as well as hotter temperatures and often declining water resource availability. These ecosystems are some of the most challenging to monit...
Global patterns and regional insights into kelp forest protection, restoration, and stewardshipNARA Subscribed
Kelp forests are among the most extensive and productive coastal ecosystems, yet they remain underrepresented in global conservation policy despite widespread declines driven by interacting global- (i.e., ocean warming, marine heatwaves) to local-scale stressors. At the same time, kelp conservation and restoration efforts are expanding rapidly across regions, but measures of success and syntheses tend to primarily focus on eco...
Facilitation in plant communities – special issue editorialNARA Subscribed
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Exploring Marine Mammal Cognition as a Conservation ToolNARA Subscribed
Cognition is an animal's real‐time adaptation system for responding to change. Rapid environmental change, often anthropogenic, is expanding the range and severity of challenges confronting wild animals. Effective conservation requires a multifaceted approach that includes animals' capacities. Large‐brained, long‐lived animals such as marine mammals often have extensive capability to adaptively modify their behavior due to the...
Spatiotemporal Patterns and Drivers of Fish Biodiversity on a Remote Freshwater ArchipelagoNARA Subscribed
Aim Fish communities are shaped by environmental filters operating across different spatiotemporal scales. While many recent studies focus on anthropogenic gradients, few can isolate the role of natural drivers in community assembly. Isle Royale's inland lakes offer a rare opportunity to explore long‐term fish biodiversity dynamics with minimal confounding influences. We analysed fish communities in 23 lakes surveyed in the 19...
Co-Encapsulation of Doxorubicin HCl and Paclitaxel in Nanovesicles for Enhanced Breast Cancer TherapyNARA Subscribed
Breast cancer is a prevalent malignancy that can metastasize to distant organs if left untreated, leading to significant morbidity. While chemotherapy is commonly used, it has drawbacks like low tissue availability, short circulation time, and toxicity to healthy cells. The objective of this study was to develop and characterize three different nanovesicles loaded with doxorubicin hydrochloride and paclitaxel, hypothesizing th...
Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout ( Salvelinus namaycush ) acclimatized to winter and summer temperatures to determine the extent to which they seasonally adjust cardiac thermal performance and adrenergic control. We...