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Free Fatty acid-induced disruption of hepatic vitamin D metabolism impairs bone homeostasis in an in vitro 3D human liver–bone modelNARA Subscribed
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a systemic condition associated with compromised bone integrity. Emerging evidence suggests that disturbances in hepatic vitamin D metabolism may contribute to these skeletal impairments. However, the hepatic mechanisms driving bone deterioration remain poorly defined. This study aimed to establish a human 3D in vitro model of MASLD and demonstrate that hepati...
Purpose Social aspects are increasingly recognized as a standard component of sustainability. Social Life Cycle Assessment (S-LCA) is a technique to address this. The analysis of social acceptance points in a similar direction and is, among others, important to develop socially responsible products – but can they go hand in hand? This research explores the relationship between S-LCA and social acceptance in literature. The fun...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
Oscillatory Dynamics Serving Verbal Working Memory Differ in People with HIV and Are Linked To Disease DurationNARA Subscribed
Background Medical advances have greatly improved the quality of life and extended the longevity of people with HIV (PWH). However, many PWH still develop neurocognitive deficits even in the presence of effective viral suppression, with impairments in verbal working memory (VWM) being among the most common. While previous neuroimaging studies have demonstrated altered neural responses during VWM, the underlying temporal dynami...
PSILCA database for social life cycle assessment: worker hours vs. raw values approachNARA Subscribed
Purpose Progressive development within the research area of social life cycle assessment (S-LCA) has recently occurred, for example, GreenDelta introduced a new direct quantification approach using raw values in the PSILCA database. This complements the concept of the activity variable worker hours, which has many advantages and disadvantages. This paper aims to assess this new approach by identifying its characteristics, oppo...
Establishment of a human 3D in vitro liver-bone model as a potential system for drug toxicity screeningNARA Subscribed
Drug toxicity is an important cause of chronic liver damage, which in the long term can lead to impaired bone homeostasis through an imbalance in the liver-bone axis. For instance, non-steroidal anti-inflammatory drugs ( e.g., diclofenac), which are commonly used to control pain during orthopaedic interventions, are known to reduce bone quality and are the most prevalent causes of drug-induced liver damage. Therefore, we used...
SNAPSHOT USA 2019–2023: The First Five Years of Data From a Coordinated Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multicontributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of specie...
183 Effects of prolonged hay net feeding on equine behaviorNARA Subscribed
Genomic time‐series data show that gene flow maintains high genetic diversity despite substantial genetic drift in a butterfly speciesNARA Subscribed
Effective population size affects the efficacy of selection, rate of evolution by drift and neutral diversity levels. When species are subdivided into multiple populations connected by gene flow, evolutionary processes can depend on global or local effective population sizes. Theory predicts that high levels of diversity might be maintained by gene flow, even very low levels of gene flow, consistent with species long‐term effe...
Purpose Gold extraction in the Amazonian rainforest is accompanied by ecological threats and social grievances, but at the same time, the artisanal small-scale gold mining sector (ASGM) provides a livelihood for many people. To address this tradeoff, this paper analyzed the social aspects and their possible relations by conducting a case study based on a Social Life Cycle Assessment (SLCA). This study seeks to determine whethe...