The Alphacoronavirus ‐ 1 species include viruses that infect numerous mammalian species. To better understand the wide host range of these viruses, better knowledge on the molecular determinants of virus–host cell entry mechanisms in wildlife hosts is essential. We investigated Alphacoronavirus ‐ 1 infection in carnivores using long‐term data on Serengeti spotted hyenas ( Crocuta crocuta ) and molecular analyses guided by the...