Summary The human nasal passage, from the anterior nares through the nasal vestibule to the nasal cavities, is an important habitat for opportunistic pathogens and commensals alike. This work sampled four different anatomical regions within the human nasal passage across a large cohort of individuals ( n = 79) comprising individuals suffering from chronic nasal inflammation clinically known as chronic rhinosinusitis (CRS) and...

Summary The complex anatomy of the human nose might offer distinct microbial niches. Microbiota composition may affect nose inflammatory diseases and S taphylococcus aureus carriage. Considering different nasal cavity locations, microbial colonization was analysed across individuals exhibiting chronic nasal inflammatory diseases ( n = 18) and those without local inflammation signs ( n = 16). Samples were collected systematical...

Summary The anterior nares are an important reservoir for opportunistic pathogens and commensal microorganisms. A barcoded I llumina paired‐end sequencing method targeting the 16 S ribosomal RNA V 1‐2 hypervariable region was developed to compare the bacterial diversity of the anterior nares across distinct human populations (volunteers from G ermany vs a B abongo P ygmy tribe, A frica). Of the 251 phylotypes detected, 231 cou...