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Cancer Causes & Control · 2024 · Vol. 35 · Issue 1 · Springer
Background Subsequent primary neoplasms (SPN) are among the most severe late effects and the second most frequent cause of death in childhood cancer patients. In this paper we introduce method and properties of the STATT-SCAR study (Second Tumor After Tumor Therapy, Second Cancer After Radiotherapy), which is a joint nested matched case–control study to evaluate the impact of chemotherapy (STATT) as well as radiotherapy (SCAR)...
Stochastic Environmental Research and Risk Assessment · 2021 · Vol. 35 · Issue 6 · Springer
Perfluorooctanoic acid (PFOA) and related chemicals among the per- and polyfluoroalkyl substances are widely distributed in the environment. Adverse health effects may occur even at low exposure levels. A large-scale contamination of drinking water resources, especially the rivers Möhne and Ruhr, was detected in North Rhine-Westphalia, Germany, in summer 2006. As a result, concentration data are available from the water supply...
Journal of Molecular Medicine · 2021 · Vol. 99 · Issue 2 · Springer
Developing resistance mechanisms of pathogens against established and frequently used drugs are a growing global health problem. Besides the development of novel drug candidates per se, new approaches to counteract resistance mechanisms are needed. Drug candidates that not only target the pathogens directly but also modify the host immune system might boost anti-parasitic defence and facilitate clearance of pathogens. In this...
Standort · 2020 · Vol. 44 · Issue 4 · Springer
Zusammenfassung Der Beitrag entwickelt die Perspektive einer kritischen Lehre zum Thema Nachhaltigkeit und zeigt deren Relevanz für die spätere Berufspraxis von Geograph*innen auf. Es wird diskutiert, inwiefern ein komplexes und kritisches Verständnis von Nachhaltigkeit zielführend zu einer transformativen Lehrpraxis weiterentwickelt werden kann. Kritische Lehre entsteht aus unserer Sicht aus der Verbindung von drei zentralen...