Keith Edwards results 114
· Newest (Page 1/5, per page 25)
Author: Keith Edwards ×Clear All Filters
Search Results
The Toxicology Investigators Consortium 2023 Annual ReportNARA Subscribed
Mouse models with complex genetic backgrounds are increasingly used in preclinical research to accurately model human disease and to enable temporal and cell-specific evaluation of genetic manipulations. Backcrossing mice onto these complex genetic backgrounds takes time and leads to significant wastage of animals. In this study, we aimed to evaluate whether site-specific nucleases could be used to generate additional genetic...
2022 marked the third consecutive La Niña and extended the longest consecutive stretch of negative Oceanic Niño Index since 1998-2001. While physical and biological conditions in winter and spring largely adhered to prior La Niña conditions, summer and fall were very different. Similar to past La Niña events, in winter and spring coastal upwelling was either average or above average, temperature average or below average, salin...
The Toxicology Investigators Consortium 2022 Annual ReportNARA Subscribed
Mechanisms and models for industry engagement in collaborative research in commercial fisheriesOA Marine
Data and insights from fishers are essential sources of information to advance understanding of fishery and ecosystem dynamics. Incorporating fisher and industry knowledge holds prospects for improving marine science and fisheries management. We address cooperative research in the context of collaboration between fishers, scientists, industries, universities, and agencies to develop applied research to understand marine ecosys...
Prediction of near‐term climate change impacts on UK wheat quality and the potential for adaptation through plant breedingNARA Subscribed
Wheat is a major crop worldwide, mainly cultivated for human consumption and animal feed. Grain quality is paramount in determining its value and downstream use. While we know that climate change threatens global crop yields, a better understanding of impacts on wheat end‐use quality is also critical. Combining quantitative genetics with climate model outputs, we investigated UK‐wide trends in genotypic adaptation for wheat qu...
High summer temperatures are associated with poorer performance of underyearling Atlantic salmon ( Salmo salar ) in upland streamsNARA Subscribed
Future warming scenarios are predicted to result in an increased frequency of high, and potentially stressful, temperatures in aquatic ecosystems. Here we examined whether the performance of wild underyearling Atlantic salmon ( Salmo salar ) in Scottish streams stocked with identical egg densities was influenced by thermal stress. Biomass and density declined with degree hours exceeding 23°C, indicating apparent mortality or e...
In late 2020, models predicted that a strong La Niña would take place for the first time since 2013, and we assessed whether physical and biological indicators in 2021 were similar to past La Niñas in the California Current Ecosystem (CCE). The Pacific Decadal Oscillation and Oceanic Niño Index indeed remained negative throughout 2021; the North Pacific Gyre Oscillation Index, however, remained strongly negative. The seventh l...
Aim Migratory freshwater fishes are those that must access discrete habitats to complete their life cycles. Freshwater fish migrations occur around the world and provide numerous ecosystem services for humans and natural systems; however, many migratory species are in decline globally. A limiting factor to successfully conserve freshwater migratory fishes is that the migratory life histories of many species are unknown or only...