Kenneth Chang results 40
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Monitoring evapotranspiration to link agricultural water use with crop yield at sub-field scalesNARA Subscribed
Purpose Scientists and producers have pursued precision agriculture to increase yields and limit environmental impacts. Applying precision agriculture concepts has not been straightforward, however, because complex interactions between soil and weather govern crop growth. We hypothesize that evapotranspiration (ET) is a single metric that captures interactions between plant status, soil, topography, and weather and can be used...
Functional effects of subsidies and stressors on benthic microbial communities along freshwater to marine gradientsNARA Subscribed
Leaf litter in coastal wetlands lays the foundation for carbon storage, and the creation of coastal wetland soils. As climate change alters the biogeochemical conditions and macrophyte composition of coastal wetlands, a better understanding of the interactions between microbial communities, changing chemistry, and leaf litter is required to understand the dynamics of coastal litter breakdown in changing wetlands. Coastal wetla...
Non-clinical Pharmacology of YTX-7739: a Clinical Stage Stearoyl-CoA Desaturase Inhibitor Being Developed for Parkinson’s DiseaseNARA Subscribed
Summary Stearoyl-CoA desaturase (SCD) is a potential therapeutic target for Parkinson’s and related neurodegenerative diseases. SCD inhibition ameliorates neuronal toxicity caused by aberrant α-synuclein, a lipid-binding protein implicated in Parkinson’s disease. Its inhibition depletes monounsaturated fatty acids, which may modulate α-synuclein conformations and membrane interactions. Herein, we characterize the pharmacokinet...