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The effect of enhanced glycolysis on cardiac agingNARA Subscribed
Cardiac aging is associated with metabolic changes, including an increased reliance on glycolysis, and an increased susceptibility to cardiovascular diseases. This study explores the relationship between enhanced cardiac glycolysis and aging using the Glyco Hi mouse model, characterized by constitutively elevated glycolysis. We compared cardiac function, metabolism, mitochondrial performance, and hallmarks of aging between age...
We contend that ocean turbulent fluxes should be included in the list of Essential Ocean Variables (EOVs) created by the Global Ocean Observing System. This list aims to identify variables that are essential to observe to inform policy and maintain a healthy and resilient ocean. Diapycnal turbulent fluxes quantify the rates of exchange of tracers (such as temperature, salinity, density or nutrients, all of which are already EO...
The loss of cardiac SIRT3 decreases metabolic flexibility and proteostasis in an age-dependent mannerNARA Subscribed
SIRT3 is a longevity factor that acts as the primary deacetylase in mitochondria. Although ubiquitously expressed, previous global SIRT3 knockout studies have shown primarily a cardiac-specific phenotype. Here, we sought to determine how specifically knocking out SIRT3 in cardiomyocytes (SIRTcKO mice) temporally affects cardiac function and metabolism. Mice displayed an age-dependent increase in cardiac pathology, with 10-mont...
We test a newly developed instrument prototype which utilizes time-resolved chlorophyll- a fluorescence techniques and fluctuating light to characterize Symbiodiniaceae functional traits across seven different coral species under cultivation as part of ongoing restoration efforts in the Florida Keys. While traditional chlorophyll- a fluorescence techniques only provide a handful of algal biometrics, the system and protocol we...
Seasonality of dissolved organic matter in lagoon ecosystems along the Alaska Beaufort Sea coastNARA Subscribed
Seasonal variations in dissolved organic matter (DOM) fluxes from land to sea have been well documented in the Arctic, yet remarkably little is known about how DOM varies seasonally within Arctic coastal waters. This is particularly true for shallow inshore environments. Here we document seasonality of DOM in lagoons along the eastern Alaska Beaufort Sea coast during the spring ice break‐up (June), summer open‐water (August),...
Discovery of a major QTL for root-knot nematode (Meloidogyne incognita) resistance in cultivated sweetpotato (Ipomoea batatas)NARA Subscribed
Key message Utilizing a high-density integrated genetic linkage map of hexaploid sweetpotato, we discovered a major dominant QTL for root-knot nematode (RKN) resistance and modeled its effects. This discovery is useful for development of a modern sweetpotato breeding program that utilizes marker-assisted selection and genomic selection approaches for faster genetic gain of RKN resistance. Abstract The root-knot nematode [Meloi...
Optimizing nitrogen (N) management is an important factor for sustainable perennial biomass systems. However, N application is costly, both financially and environmentally. Our objectives were to determine: (1) N rate and plant spacing effects on yield and yield components of prairie cordgrass swards and (2) fertilizer N replacement value (FNRV) of kura clover in prairie cordgrass-kura clover binary mixtures. Plots were establ...
Age‐specific vibrissae growth rates: A tool for determining the timing of ecologically important events in Steller sea lionsNARA Subscribed
Steller sea lions ( SSL ; Eumetopias jubatus ) grow their vibrissae continually, providing a multiyear record suitable for ecological and physiological studies based on stable isotopes. An accurate age‐specific vibrissae growth rate is essential for registering a chronology along the length of the record, and for interpreting the timing of ecologically important events. We utilized four methods to estimate the growth rate of v...