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NARA Subscribed1
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Springer Nature1
Journal
Pflügers Archiv - European Journal of Physiology1
Publication Year
20211
Kento Kitada results 1 · Newest (Page 1/1, per page 25)
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Author: Kento Kitada ×Clear All Filters
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Abnormal neonatal sodium handling in skin precedes hypertension in the SAME ratNARA Subscribed
Pflügers Archiv - European Journal of Physiology · 2021 · Vol. 473 · Issue 6 · Springer
Linda Mullins; Jessica Ivy; Mairi Ward; Olav Tenstad; Helge Wiig; Kento Kitada; Jon Manning; Natalia Rakova; Dominik Muller; John Mullins
We discovered high Na + and water content in the skin of newborn Sprague–Dawley rats, which reduced ~ 2.5-fold by 7 days of age, indicating rapid changes in extracellular volume (ECV). Equivalent changes in ECV post birth were also observed in C57Bl/6 J mice, with a fourfold reduction over 7 days, to approximately adult levels. This established the generality of increased ECV at birth. We investigated early sodium and water ha...
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