This paper considers a target-defense game in an open area with one or two defenders as well as an intruder. The intruder endeavors to reach the boundary of the island, while the defenders strive to prevent that by capturing the intruder through contact. Islands, as closed areas, restrict the free movement of the defenders, since the defenders—represented by USVs—cannot traverse the target area directly. First, we are concerne...

Idiopathic pulmonary fibrosis (IPF) is a progressive fatal interstitial lung disease that affects three million patients worldwide and currently without an effective cure. Zinpentraxin alfa, a recombinant human pentraxin-2 (rhPTX-2) protein, has been evaluated as a potential drug candidate for the treatment of IPF. Clinical pharmacokinetic analysis of zinpentraxin alfa has been challenging historically due to interference from...