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Germ cell-specific gene 2 accelerates cell cycle in epithelial ovarian cancer by inhibiting GSK3α-p27 cascadeNARA Subscribed
Epithelial ovarian cancer (EOC) is one of the most common malignant gynecological tumors with rapid growth potential and poor prognosis, however, the molecular mechanism underlying its outgrowth remained elusive. Germ cell-specific gene 2 (GSG2) was previously reported to be highly expressed in ovarian cancer and was essential for the growth of EOC. In this study, GSG2-knockdown cells and GSG2-overexpress cells were establishe...
A three-dimensional experimental study on bank retreat: The coupled role of seepage and surface flowOA Marine
The coupled role of seepage and surface flow on bank retreat has long been neglected, partly due to the concealment and complexity of seepage erosion. To fill this gap, we set up a three-dimensional laboratory experiment to explore bank retreat process in response to seepage and surface flow. During each experiment, we measured the changes of total soil stress, matric suction, and water content within the bank, as well as flow...
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