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AAPS PharmSciTech · 2019 · Vol. 20 · Issue 3 · Springer
The aim of this study is to investigate the dissolution properties of poorly soluble drugs from their pure form and their amorphous formulation under physiological relevant conditions for oral administration based on surface dissolution ultraviolet (UV) imaging. Dissolution of two poorly soluble drugs (cefuroxime axetil and itraconazole) and their amorphous formulations (Zinnat ® and Sporanox ® ) was studied with the Sirius Su...