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Springer Nature5
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Pharmaceutical Research3
The AAPS Journal2
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Kunal S. Taskar results 5 · Newest (Page 1/1, per page 25)
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PBPK Modelling of PROTACs: Learnings from ARV-110 as a Case ExampleNARA Subscribed
The AAPS Journal · 2026 · Vol. 28 · Issue 3 · Springer
Farzaneh Salem; Ali Tabatabaeian Nimavardi; Abhishek Srivastava; Katharina Krollik; Andreas Reichel; David Cebrian; Kunal S. Taskar; James W. T. Yates; Caroline Rynn; Heide Marika Duevel
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PBPK Modelling of Antisense Oligonucleotide Therapeutics: Application for Predicting Plasma and Tissue Pharmacokinetics of BepirovirsenNARA Subscribed
The AAPS Journal · 2026 · Vol. 28 · Issue 2 · Springer
Farzaneh Salem; Felix Stader; Amir S. Youssef; Abdallah Derbalah; Ahmed Nader; Steve Hood; Kunal Taskar
Antisense oligonucleotide (ASO) therapeutics present new opportunities for treating challenging-to-treat diseases. Prediction of concentration–time course in systemic circulation and tissues within the context of large molecule physiologically based pharmacokinetic (PBPK) modelling has proven to be useful in animal-to-human extrapolation and first-in-human dose selection. A human PBPK model was developed and verified using bep...
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Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast CancerNARA Subscribed
Pharmaceutical Research · 2016 · Vol. 33 · Issue 12 · Springer
Ramakrishna Samala; Helen R. Thorsheim; Satyanarayana Goda; Kunal Taskar; Brunilde Gril; Patricia S. Steeg; Quentin R. Smith
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Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast CancerNARA Subscribed
Pharmaceutical Research · 2012 · Vol. 29 · Issue 3 · Springer
Kunal S. Taskar; Vinay Rudraraju; Rajendar K. Mittapalli; Ramakrishna Samala; Helen R. Thorsheim; Julie Lockman; Brunilde Gril; Emily Hua; Diane Palmieri; Joseph W. Polli; Stephen Castellino; Stephen D. Rubin; Paul R. Lockman; Patricia S. Steeg; Quentin R. Smith
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Uptake of ANG1005, A Novel Paclitaxel Derivative, Through the Blood-Brain Barrier into Brain and Experimental Brain Metastases of Breast CancerNARA Subscribed
Pharmaceutical Research · 2009 · Vol. 26 · Issue 11 · Springer
Fancy C. Thomas; Kunal Taskar; Vinay Rudraraju; Satyanarayana Goda; Helen R. Thorsheim; Julie A. Gaasch; Rajendar K. Mittapalli; Diane Palmieri; Patricia S. Steeg; Paul R. Lockman; Quentin R. Smith
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