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Deviations from additivity in APOE4-mediated late-onset Alzheimer’s disease risk across races and ethnicitiesNARA Subscribed
APOE ’s ε4 haplotype ( APOE4 ) is late onset Alzheimer’s disease’s (LOAD) strongest genetic risk factor. Therefore, accurately modeling APOE4 ’s effect is critical to understanding LOAD. This is especially important as APOE4 odds ratios (OR) vary across racial and ethnic (R/E) groups. We analyzed the APOE4 -LOAD association in 3,196 East Asian, 31,105 non-Hispanic White (White), 1,646 Hispanic and Latino (Hispanic), and 6,068...
Age, growth and sexual dimorphism of the monkeyface prickleback ( Cebidichthys violaceus )NARA Subscribed
Accurate estimates of age, growth and maturation are fundamental to fisheries assessment, conservation and the development of emerging aquaculture species. However, life‐history parameters can vary within species and may be influenced by factors such as sexual dimorphism, which is often poorly quantified in non‐commercial or understudied species. The monkeyface prickleback ( Cebidichthys violaceus ), one of the largest herbivo...
Insect communities of late Pleistocene steppe–tundra and Holocene boreal forest ecosystems in central Yukon Territory, CanadaNARA Subscribed
Subfossil insect communities from the Quartz Creek site provide a detailed record of both Late Pleistocene steppe–tundra and Holocene boreal forest ecosystems in central Yukon Territory, Canada. Fifteen Pleistocene assemblages (marine isotope stages [MIS] 4 to 2) are dominated by steppe–tundra and dry‐tundra taxa, particularly the weevils Connatichela artemisiae and Lepidophorus lineaticollis , indicating a cold and dry enviro...
Synergistic Interactions Between Warming and Elevated Atmospheric CO 2 Increase Soil Organic Carbon SequestrationNARA Subscribed
Warming and elevated CO 2 (eCO 2 ) are two potentially opposing climate‐carbon (C) feedback mechanisms that modulate the magnitude of the land C sink, with warming decreasing and eCO 2 increasing C sequestration. However, their net effect on soil organic C (SOC)—the largest terrestrial C stock—remains uncertain. Here, we quantify how warming, eCO 2 , and their interactions influence SOC by using 5558 paired observations from 1...