L. Crowe results 46
· Newest (Page 1/2, per page 25)
Author: L. Crowe ×Clear All Filters
Search Results
Mating systems, parentage, and reproductive success of beluga whales in Bristol Bay, AlaskaOA Marine
An aquatic mode of life and sociality influences mating strategies in cetaceans. In high latitude species, like the beluga whale, extreme seasonality likely imposes additional constraints on parental care, competition, and mate choice. Genetic profiling of 623 biopsy-sampled beluga whales in Bristol Bay, Alaska revealed that both sexes were polygamous, calves associated predominantly with their mothers, variation in reproducti...
Exposure and behavioral responses of tagged beluga whales ( Delphinapterus leucas ) to ships in the Pacific ArcticNARA Subscribed
Arctic marine mammals face a multitude of challenges linked to climate change, including increasing anthropogenic noise from ship traffic. The beluga whale ( Delphinapterus leucas ), a predominately Arctic endemic cetacean, relies heavily on acoustic communication, with documented overlap between their vocalizations and hearing range and ship noise. Some belugas migrate through areas with the highest levels of ship traffic in...
Targeting de novo loss-of-function variants in constrained disease genes improves diagnostic rates in the 100,000 Genomes ProjectNARA Subscribed
Background Genome sequencing was first offered clinically in the UK through the 100,000 Genomes Project (100KGP). Analysis was restricted to predefined gene panels associated with the patient’s phenotype. However, panels rely on clearly characterised phenotypes and risk missing diagnoses outside of the panel(s) applied. We propose a complementary method to rapidly identify pathogenic variants, including those missed by 100KGP...
About a third of all marine fish in the world are caught in Small-Scale Fisheries (SSF). SSF are increasingly recognised as essential for food security and livelihoods for vulnerable and economically fragile communities globally. Although individual SSF vessels are usually perceived as having little impact on the ecosystem, the cumulative impact of gear type and number of vessels may be substantial. Bottom trawling is a common...
The critically endangered North Atlantic right whale population ( Eubalaena glacialis ) has experienced multiple periods of decreased reproduction within its observable history, which have played a role in the overall decline of the species. In addition to this synchronized variation in reproduction across the population, there exists considerable individual variation in fecundity. To determine the impacts of family history an...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Origin and expansion of the world’s most widespread pinniped: Range‐wide population genomics of the harbour seal ( Phoca vitulina )NARA Subscribed
The harbour seal ( Phoca vitulina ) is the most widely distributed pinniped, occupying a wide variety of habitats and climatic zones across the Northern Hemisphere. Intriguingly, the harbour seal is also one of the most philopatric seals, raising questions as to how it colonized its current range. To shed light on the origin, remarkable range expansion, population structure and genetic diversity of this species, we used genoty...
Dive behavior represents multiple ecological functions for marine mammals, but our understanding of dive characteristics is typically limited by the resolution or longevity of tagging studies. Knowledge on the time-depth structures of dives can provide insight into the behaviors represented by vertical movements; furthering our understanding of the ecological importance of habitats occupied, seasonal shifts in activity, and th...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Functional redundancy imparts process stability to acidic Fe( II )‐oxidizing microbial reactorsNARA Subscribed
Summary In previous work, lab‐scale reactors designed to study microbial Fe(II) oxidation rates at low pH were found to have stable rates under a wide range of pH and Fe(II) concentrations. Since the stirred reactor environment eliminates many of the temporal and spatial variations that promote high diversity among microbial populations in nature, we were surprised that the reactors supported multiple taxa presumed to be autot...
Mortality is a demographic metric crucial for understanding the dynamics of endangered populations such as Cook Inlet beluga whales (CIBWs, Delphinapterus leucas ), but patterns of mortality are currently not well understood for CIBWs, making decisions about recovery actions challenging. We combined long‐term photo‐ID data from approximately 420 individual belugas identified during the period 2005–2017 with stranding data from...
A global analysis of complexity–biodiversity relationships on marine artificial structuresNARA Subscribed
Aim Topographic complexity is widely accepted as a key driver of biodiversity, but at the patch‐scale, complexity–biodiversity relationships may vary spatially and temporally according to the environmental stressors complexity mitigates, and the species richness and identity of potential colonists. Using a manipulative experiment, we assessed spatial variation in patch‐scale effects of complexity on intertidal biodiversity. Lo...
Phototactic tails: Evolution and molecular basis of a novel sensory trait in sea snakesNARA Subscribed
Dermal phototaxis has been reported in a few aquatic vertebrate lineages spanning fish, amphibians and reptiles. These taxa respond to light on the skin of their elongate hind‐bodies and tails by withdrawing under cover to avoid detection by predators. Here, we investigated tail phototaxis in sea snakes (Hydrophiinae), the only reptiles reported to exhibit this sensory behaviour. We conducted behavioural tests in 17 wild‐caugh...