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NARA Subscribed1
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Springer Nature1
Journal
Molecular Genetics and Genomics1
Publication Year
20261
L. Dunlay results 1 · Newest (Page 1/1, per page 25)
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Author: L. Dunlay ×Clear All Filters
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Genetic-epigenetic interactions (meQTLs) in orofacial clefts etiologyNARA Subscribed
Molecular Genetics and Genomics · 2026 · Vol. 301 · Issue 1 · Springer
A. L. Petrin; L. A. Machado-Paula; H. L. Keen; L. Hovey; B. Doolittle; L. Dunlay; W. Awotoye; X. J. Xie; E. Zeng; A. Butali; M. L. Marazita; J. C. Murray; L. M. Moreno-Uribe
Understanding how genetic variants influence disease risk through molecular mechanisms remains a central challenge in complex disease genetics. Nonsyndromic orofacial clefts (OFCs) exemplify this challenge, with most risk loci residing in non-coding regions. We hypothesized that common genetic variants influence OFC risk by modulating DNA methylation at regulatory elements through methylation quantitative trait loci (meQTLs)....
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