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Congressionally designated wilderness offers the highest level of land protection in the USA, comparable to category 1b wilderness as defined by the International Union for Conservation of Nature, yet wilderness areas face impacts of climate change. Researchers and managers increasingly recognize the immense challenge of stewarding wilderness in a changing climate. Although responding to climate change is considered a wicked p...
Expanding insights into plant rhabdovirus diversity through the discovery of viruses representing 32 putative novel speciesNARA Subscribed
Plant-infecting rhabdoviruses (family Rhabdoviridae , subfamily Betarhabdovirinae ) include several viruses that cause important crop diseases and are subject to phytosanitary regulation. Despite their agricultural and ecological importance, the diversity of plant rhabdoviruses and their impact on plant health remain poorly understood. Here, we report 32 tentative novel species of plant-infecting rhabdoviruses, identified via...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Assessing direct effects of insect change on insectivore populations in the United KingdomNARA Subscribed
Declines in insect abundance are a cause for concern, with potential downstream impacts on ecosystem function. Insects are key food resources for insectivorous vertebrates, with evidence that reductions in prey availability may influence population dynamics. Yet quantifying direct effects at large spatial scales is difficult, both due to data limitations and because correlations may reflect shared responses to environmental ch...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Boost or Bust? The Impact of Supplementation on Functional Genetic Diversity and Selective Processes in Tasmanian DevilsNARA Subscribed
Translocating individuals into existing populations of conspecifics can support threatened species by increasing population size, maintaining genetic diversity and reducing the risk of inbreeding. However, for species whose adaptive potential is compromised due to ongoing threats, like disease, the outcome of such management interventions becomes more complex. The Tasmanian devil ( Sarcophilus harrisii ) is a prime example, wh...
Climate change impacts to upwelling and shallow reef nutrient sources across an oceanic archipelagoNARA Subscribed
Upwelling delivers key nutritional and energetic subsidies to coral reef communities that affect the growth, abundance, and ecology of organisms across trophic levels. However, the cross‐scale oceanographic and atmospheric drivers of localized upwelling on many reefs remain unresolved, limiting our ability to predict how climate change might disrupt upwelling patterns and impact reef communities across geographies. Using high...
Temporal Changes in Tasmanian Devil Genetic Diversity at Sites With and Without SupplementationNARA Subscribed
Management interventions for threatened species are well documented with genetic data now playing a pivotal role in informing their outcomes. However, in situ actions like supplementations (releasing individuals into an existing population) are often restricted to a singular site. Considerable research and management effort have been dedicated to conserving the Tasmanian devil ( Sarcophilus harrisii ), offering a unique opport...