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NARA Subscribed1
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Springer Nature1
Journal
Human Genetics1
Publication Year
20221
L. M. Raffield results 1 · Newest (Page 1/1, per page 25)
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Author: L. M. Raffield ×Clear All Filters
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Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferationNARA Subscribed
Human Genetics · 2022 · Vol. 141 · Issue 1 · Springer
R. J. Longchamps; S. Y. Yang; C. A. Castellani; W. Shi; J. Lane; M. L. Grove; T. M. Bartz; C. Sarnowski; C. Liu; K. Burrows; A. L. Guyatt; T. R. Gaunt; T. Kacprowski; J. Yang; P. L. De Jager; L. Yu; A. Bergman; R. Xia; M. Fornage; M. F. Feitosa; M. K. Wojczynski; A. T. Kraja; M. A. Province; N. Amin; F. Rivadeneira; H. Tiemeier; A. G. Uitterlinden; L. Broer; J. B. J. Van Meurs; C. M. Van Duijn; L. M. Raffield; L. Lange; S. S. Rich; R. N. Lemaitre; M. O. Goodarzi; C. M. Sitlani; A. C. Y. Mak; D. A. Bennett; S. Rodriguez; J. M. Murabito; K. L. Lunetta; N. Sotoodehnia; G. Atzmon; K. Ye; N. Barzilai; J. A. Brody; B. M. Psaty; K. D. Taylor; J. I. Rotter; E. Boerwinkle; N. Pankratz; D. E. Arking
Mitochondrial DNA copy number (mtDNA-CN) measured from blood specimens is a minimally invasive marker of mitochondrial function that exhibits both inter-individual and intercellular variation. To identify genes involved in regulating mitochondrial function, we performed a genome-wide association study (GWAS) in 465,809 White individuals from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium a...
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