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COVID-19 vaccination shifts neutrophils toward a mixed activated and regulatory phenotype in patients with severe diseaseNARA Subscribed
Background Dysregulation of the innate immune response to SARS-CoV-2 has been linked to poor outcomes in COVID-19. Neutrophils are key players in this response, displaying distinct functional profiles associated with disease severity. This study investigates how neutrophil phenotypes, and their mediators are modulated in severe COVID-19 following vaccination. Methods and Results We conducted an observational case-control study...
Small carnivores, such as the Pallas’s cat ( Otocolobus manul ), play important ecological roles but remain poorly studied in many parts of their range, particularly in landscapes undergoing rapid human-induced change. We investigated Pallas’s cat occupancy and activity patterns in Bogd Khan Mountain, north-central Mongolia, in relation to habitat features, camera-detectable potential prey activity, and anthropogenic disturban...
Microplastic Pollution in High-Elevation Water Bodies of the Serra da Estrela Mountain Range, PortugalNARA Subscribed
Microplastics—synthetic particles ranging in size from 1 μm to 5 mm—are now widely recognised as an emerging environmental issue due to their ubiquity across ecosystems. While most research has focused on marine environments, important knowledge gaps remain regarding their occurrence in freshwater systems, particularly in remote and high-altitude ecosystems. Given the increasing human use of these environments, understanding p...
Hedgehogs represent a promising indicator for evaluating environmental health. We investigated the occurrence of third-generation cephalosporin-resistant (3GCR) Escherichia coli in intestinal contents from 49 European hedgehogs ( Erinaceus europaeus ) deceased at a Wildlife Rescue Centre in Lombardy, Northern Italy. Bacteriological analysis was performed to isolate 3GCR- E. coli ; antimicrobial-resistance (AMR) profiles of the...
Iron is an essential micronutrient for brain development, participating in mitochondrial respiration, myelination, and neurotransmitter synthesis. However, previous studies have demonstrated that excessive iron during early postnatal life induces oxidative reactions, leading to mitochondrial dysfunction and synaptic failure. These alterations compromise energy metabolism and neuronal integrity, contributing to long-lasting cog...