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Genetic diversity and historical demography of the imperiled rattlesnake-master borer moth (Papaipema eryngii)NARA Subscribed
Large-scale habitat loss and degradation have triggered a global biodiversity crisis with ecological-specialist species at increased risk of extinction. The Rattlesnake-Master Borer ( Papaipema eryngii ) is a small noctuid moth whose larvae feed exclusively on rattlesnake master ( Eryngium yuccifolium ), a native grassland plant ranging throughout the eastern United States. Widespread loss of grassland habitats has resulted in...
Climate change is altering species’ range limits and transforming ecosystems. For example, warming temperatures are leading to the range expansion of tropical, cold-sensitive species at the expense of their cold-tolerant counterparts. In some temperate and subtropical coastal wetlands, warming winters are enabling mangrove forest encroachment into salt marsh, which is a major regime shift that has significant ecological and so...
Climate change is transforming ecosystems and affecting ecosystem goods and services. Along the Gulf of Mexico and Atlantic coasts of the southeastern United States, the frequency and intensity of extreme freeze events greatly influence whether coastal wetlands are dominated by freeze‐sensitive woody plants (mangrove forests) or freeze‐tolerant grass‐like plants (salt marshes). In response to warming winters, mangroves have be...
Local Treatment of Non-small Cell Lung Cancer with a Spray-Dried Bevacizumab FormulationNARA Subscribed
Local delivery of biotherapeutics to the lung holds great promise for treatment of lung diseases, but development of physically stable, biologically active dry powder formulations of large molecules for inhalation has remained a challenge. Here, spray drying was used to manufacture a dry powder pulmonary formulation of bevacizumab, a monoclonal antibody approved to treat non-small cell lung cancer (NSCLC) by intravenous infusi...
Legacy introductions and climatic variation explain spatiotemporal patterns of invasive hybridization in a native troutNARA Subscribed
Hybridization between invasive and native species, a significant threat to worldwide biodiversity, is predicted to increase due to climate‐induced expansions of invasive species. Long‐term research and monitoring are crucial for understanding the ecological and evolutionary processes that modulate the effects of invasive species. Using a large, multidecade genetics dataset ( N = 582 sites, 12,878 individuals) with high‐resolut...
Turn costs change the value of animal search pathsNARA Subscribed
The tortuosity of the track taken by an animal searching for food profoundly affects search efficiency, which should be optimised to maximise net energy gain. Models examining this generally describe movement as a series of straight steps interspaced by turns, and implicitly assume no turn costs. We used both empirical‐ and modelling‐based approaches to show that the energetic costs for turns in both terrestrial and aerial loc...
Risk‐Based Viable Population MonitoringNARA Subscribed
We describe risk‐based viable population monitoring, in which the monitoring indicator is a yearly prediction of the probability that, within a given timeframe, the population abundance will decline below a prespecified level. Common abundance‐based monitoring strategies usually have low power to detect declines in threatened and endangered species and are largely reactive to declines. Comparisons of the population's estimated...