In the United States, colorectal cancer (CRC) mortality rates are higher in African Americans compared to non-Hispanic whites, partly due to advanced stage cancer diagnosis. Timely CRC screening helps to increase CRC early detection and survival in this population. The objective of this monitoring study was to survey African American patients of Community Health Centers (CHC) in north Florida and to monitor CRC screening adher...

The future of how we understand and manage ecosystems largely depends on direct and continuous observations that connect local territories to planetary processes. Latin America (LATAM: Mexico, Central and South America, and the Caribbean) hosts ecosystems critical for regulating global carbon, water, and energy cycles. However, persistent underinvestment in science and technology hampers the long‐term monitoring capacity neede...

Poultry litter is widely applied as an organic fertilizer, yet concerns remain regarding the cumulative input and potential accumulation of potentially toxic elements (PTEs) in agricultural soils. This study evaluated the medium-term effects of repeated poultry litter application on pseudo-total concentrations and cumulative inputs of arsenic (As), cadmium (Cs), chromium (Cr), copper (Cu), nickel (Ni), and zinc (Zn) in an acid...

Ornithine aminotransferase (OAT), a pyridoxal 5’-phosphate (PLP)-dependent enzyme, is a key contributor to glutamine supply in cancer cells, suggesting its therapeutic potential for hepatocellular carcinoma (HCC), the most common form of liver cancer. To identify an initial set of OAT inactivators, we have tested inactivators of γ-aminobutyric acid aminotransferase (GABA-AT), a homologous PLP-dependent enzyme, with human OAT (...

Aim The assembly of tropical tree floras is complex, involving many lineage‐specific histories; however, focusing on the biogeographic history of diverse clades can reveal general patterns. We investigated the historical biogeography of the ecologically important Brazil nut clade (Lecythidoideae) to: (1) expand prior phylogenies with greater sampling of the early branching Andean‐centered subclades; (2) infer the ages and disp...

Although biomedical engineering (BME) is a profession with ethical responsibilities comparable to those in medicine, it has, until now, lacked a counterpart to the Hippocratic Oath. While professional societies have established codes of ethics for biomedical engineers, these documents lack the symbolic and ceremonial significance of an oath or pledge. By contrast, the recitation of the Hippocratic Oath, or its modern version,...

The rapid advancement of DNA sequencing technologies and computational algorithms has led to an unprecedented surge in genomic data, driven by several large-scale sequencing projects worldwide. Orthology plays a crucial role in understanding evolutionary patterns of genes and their functions. At the last Quest for Orthologs meeting (Montréal, Canada—2024), we discussed recent advances in orthology inference, with a focus on th...