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Identification of a novel isoform of Slc26a4 by single-cell RNA-sequencing of pendrin-expressing cells in the cochleaNARA Subscribed
Pathogenic variation of SLC26A 4 gene causes both Pendred syndrome (PDS) and non-syndromic enlarged vestibular aqueduct (NSEVA/DFNB4), two autosomal recessive disorders. The former accounts for approximately 6% of human genetic hearing loss, making it the second most common form of syndromic deafness after Usher syndrome, while the latter is the most common radiological malformation associated with childhood sensorineural hear...
Plastic Type and Condition Have Minimal Impact on Associated Marine Biofilm CommunitiesNARA Subscribed
The ecological impacts of plastics and their additives on marine microbiota remain unclear. We applied prokaryotic 16S rRNA gene and fungal ITS2 region amplicon sequencing, alongside shotgun metagenomic sequencing, to identify compositional and functional changes in microbial communities on marine plastic. Five common plastics, both non‐aged and artificially aged, were submerged in Auckland Harbour, Aotearoa‐New Zealand. Biofi...
Inhibitory control (IC) develops in stages from infancy through adolescence and is associated with numerous developmental disorders and learning outcomes. This study examined how neural architecture – in particular myelination – underlies brain activation patterns observed during IC tasks in a sample of 28 children aged 4–10 years old. IC was observed using reaction times during go/no-go and flanker IC tasks. Myelination was m...
Comparing environmental impacts of deep‐seabed and land‐based mining: A defensible frameworkNARA Subscribed
The crises of climate change and biodiversity loss are interlinked and must be addressed jointly. A proposed solution for reducing reliance on fossil fuels, and thus mitigating climate change, is the transition from conventional combustion‐engine to electric vehicles. This transition currently requires additional mineral resources, such as nickel and cobalt used in car batteries, presently obtained from land‐based mines. Most...
Mangroves offer vital ecological advantages including air and water filtration, coastal and estuarine habitat provision, sediment stabilization, and wave energy dissipation. Their intricate root systems play a key role in safeguarding shorelines from tsunamis and erosive storms by dissipating wave energy. Moreover, mangroves shield against boat wakes and wind-waves, thus naturally bolstering shoreline defense. Wave dissipation...