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Unsupervised serious video games on the SmartMe&You home telemonitoring platform may enable the assessment of cognitive fluctuations in older individuals, with or without cognitive deficits. Here, we tested their validity in cognitively unimpaired older adults (Healthy) and patients with mild cognitive impairment and mild to moderate dementia due to Parkinson’s disease (PDCD). Such validity was assessed using Mini-Mental State...
Penguin populations are shaped by environmental variability and local ecological pressures, yet the demographic pathways linking climate, predation, and population dynamics remain difficult to disentangle. We analyzed breeding success and population abundance of Magellanic penguins ( Spheniscus magellanicus ) at Monte León National Park, Argentina, using 15 years of reproductive data (2010–2025) and 10 years of population abun...
Rationale A major obstacle in the pre-clinical study of mood-related disorders and novel affective state therapeutic evaluation is the lack of animal models that fully recapitulate human symptomatology. Objective In this study, we developed a touchscreen-based cognitive judgement bias (CJB) task for mice. Methods In the CJB task, animals first learned to discriminate between two visual stimuli displayed on the touchscreen: one...
Sedentary behavior is a recognized and modifiable risk factor for cognitive decline and dementia across neurodegenerative conditions. This study used a smartwatch-based telemonitoring procedure combined with ecological cognitive assessment to examine whether step counts can capture sedentary behavior and its association with cognitive functioning in patients with mild cognitive impairment (ADMCI) and dementia (ADD) due to Alzh...
Lewy body disease (LBD) and Alzheimer’s disease (AD) are the most common causes of cognitive decline and dementia and are associated with characteristic alterations in resting-state electroencephalographic (rsEEG) activity. This multicenter exploratory study investigated periodic and aperiodic rsEEG features in patients with cognitive decline due to Lewy body disease (LBCD) and Alzheimer’s disease (ADCD), compared with cogniti...
Climate Vulnerability Assessments in Marine Fisheries: Taking Stock and Looking AheadNARA Subscribed
Climate Vulnerability Assessments (CVAs) are important tools for understanding and addressing the impacts of climate change on marine fisheries. Since their introduction in the 1990s, CVAs have evolved from theoretical frameworks to practical applications aimed at fostering climate‐resilient fisheries management. This review synthesises recent advancements in CVAs, focusing on methodologies, geographic applications, stakeholde...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Thermochemical conversion of waste into energy: a reviewNARA Subscribed
The increasing global energy demand, the decline in fossil fuels and the growing amount of municipal solid waste are major environmental and socioeconomic issues, calling for advanced techniques to recycle waste into energy. Here, we review the thermochemical valorization of household, industrial and agricultural waste, with focus on municipal solid waste composition, fuel production, fuel characteristics, legislation and stan...
Climate change poses significant risks to Mediterranean aquaculture, with sea surface temperature (SST) identified as a critical stressor affecting cultivated species. This study aims to assess climate-related risks for coastal aquaculture in the Valencian Community (Spain) by analyzing SST spatiotemporal variability and predicting future trends. A multi-method approach was employed, combining ARIMA models for 10-year predicti...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...