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Staphylococcus aureus is a Gram-positive coccus-type bacterium responsible for colonizing various sites of the host’s body, thus generating several pathologies such as pneumonia, osteomyelitis, endocarditis, and even cases of sepsis. Eugenol, dihydroeugenol, guaiacol, and phenol are phenolic compounds with antimicrobial activities, as is the drug metronidazole; therefore, eight substances were synthesized by coupling metronida...
Small Pelagic Fish (SPF) exhibit large fluctuations in abundance and distribution in response to environmental variability. To maintain the resilience of fishing communities and develop effective and equitable climate adaptation strategies, improved understanding of how the fishing industry responds to spatio-temporal shifts within and across SPF populations is of critical importance. In this paper, we examine the responses of...
Relative Density as a Standardizing Metric for the Development of Size-Density Management ChartsNARA Subscribed
Stand density management is central to achieving diverse silvicultural objectives. Decision-support tools in this domain range from expert opinion to sophisticated computer models that vary by forest type, region, and organization. The graphical frameworks represented by density management diagrams (DMDs) and stocking guides (SGs), collectively called size-density management charts (SDMCs), are well established and balance qua...
The Ontology of Biological Attributes (OBA)—computational traits for the life sciencesNARA Subscribed
Existing phenotype ontologies were originally developed to represent phenotypes that manifest as a character state in relation to a wild-type or other reference. However, these do not include the phenotypic trait or attribute categories required for the annotation of genome-wide association studies (GWAS), Quantitative Trait Loci (QTL) mappings or any population-focussed measurable trait data. The integration of trait and biol...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
TRY plant trait database – enhanced coverage and open accessNARA Subscribed
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodivers...
A regional scale assessment of land use/land cover and climatic changes on water and energy cycle in the upper Midwest United StatesNARA Subscribed
This study examines the relative impact of regional land‐cover/land‐use patterns and projected future climate change on hydrologic processes. Historic, present and projected future land cover data were used to drive the variable infiltration capacity (VIC) model using observed meteorological forcing data for 1983–2007 over Wisconsin (USA). The current and projected future (year 2030) land cover data were developed using the la...
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