Lewis R. results 487
· Newest (Page 1/20, per page 25)
Author: Lewis R. ×Clear All Filters
Search Results
Development of RS1-specific ACMG/AMP variant classification criteria with pilot variant curationNARA Subscribed
Gene-based therapies are being developed for retinal diseases, including RS1- related X-linked retinoschisis. Therefore it is essential to determine which variants are pathogenic and which are benign when enrolling patients. The Clinical Genome Resource (ClinGen) X-Linked Inherited Retinal Diseases (XLRD) Variant Curation Expert Panel (VCEP) brings together clinician scientists, molecular biologists, and geneticists to apply t...
Early outcomes of England's new biodiversity offset marketNARA Subscribed
Nature markets are being operationalized as a tool to address the biodiversity finance gap and achieve global biodiversity targets. However, there is limited understanding of how the outcomes of these markets align with biodiversity targets. One example is the off‐site market supporting construction projects that are required to achieve biodiversity net gain (BNG) in England. To quantify the preliminary market outcomes after 1...
Marine migration influences mercury accumulation in anadromous Arctic char ( Salvelinus alpinus )NARA Subscribed
Mercury (Hg) is a globally distributed toxic metal present in northern natural environments that biomagnifies in food webs and bioaccumulates in apex predator fish, such as Arctic char ( Salvelinus alpinus )—an iteroparous species with a circumpolar distribution. Arctic char exhibit a variety of life history types, with the migrating, anadromous life‐history type supporting many subsistence and small‐scale commercial fisheries...
Nature vs. nurture? Light availability drives phenotypic plasticity within a reef coral speciesNARA Subscribed
Scleractinian corals exhibit wide intra‐specific phenotypic variations. However, the extent to which these variations are explained by genotypic variation or phenotypic plasticity remains unclear. To elucidate this question, we devised a replicated experiment in which nine Montipora capitata coral colonies were cut into six pieces each, three of which were placed in shaded conditions (with a 73% reduction in light intensity) w...
The spring bloom is an annual event in temperate regions of the North Atlantic Ocean where the abundance of photosynthetic plankton increases dramatically. The timing and intensity of the spring bloom is dependent on underlying physical conditions that control ocean stratification and mixing. Although surface waves can be an important source of turbulent kinetic energy to the surface mixed layer, they have seldom been consider...