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Background While porcine Neonatal Pancreatic Cell Clusters (NPCCs) were potential alternative source of islets, their immaturity and heterogeneity make them inefficiently ameliorate hyperglycemia in rodents. Our previous work showed that NPCCs regress to a transitional-like state immediately after isolation and undergo dynamic transcriptional changes during short-term in vitro culture. The present study aimed to further deline...
Phylogeny and Taxonomy of the Coral Reef Maidenhair Fern Adiantum capillus‐veneris subsp. lanyuanum (Pteridaceae) in East AsiaNARA Subscribed
Adiantum capillus‐veneris is a species with a worldwide distribution, exhibiting considerable morphological variation, with several infraspecific names applied. Among these infraspecific taxa, A. capillus‐veneris subspecies lanyuanum can be easily distinguished from typical A. capillus‐veneris by its small and 1‐pinnate fronds. This form has been recorded from a few insular populations in Taiwan and Japan, typically inhabiting...
The Fukushima Daiichi Nuclear Power Plant accident released radionuclides directly into the ocean as a result of the Great East Japan Earthquake on March 11, 2011. This material has been transported across the Pacific Ocean and detected in the northeastern Pacific. We began a surface ocean 129 I monitoring program a few months after this disaster in June 2011, with samples from Scripps Pier, La Jolla, California, USA, with the...
In most animals, excess dietary energy is stored as lipids in specialized tissues, such as the liver in vertebrates or the hepatopancreas and fat body in invertebrates, which function as energy reservoirs for reproduction. In cephalopods, however, dietary energy is rapidly mobilized from the digestive gland for growth rather than stored for reproduction. How excess energy is allocated for reproduction activity in cephalopods r...
STAT3 Signaling Mediates Agomelatine Restoration of Prefrontal Cortex Synaptic Plasticity in Chronic Social Defeat Stress MiceNARA Subscribed
Major depressive disorder (MDD) is a major public health issue worldwide. It not only causes an increased socio-economic burden, but also negatively affects personal lives. It has been shown that depression leads to impairments in synaptic plasticity, such as impaired long-term potentiation (LTP) in the prefrontal cortex (PFC). A recent study reported that administration of agomelatine, a melatonin receptor agonist and 5-hydro...