Background While porcine Neonatal Pancreatic Cell Clusters (NPCCs) were potential alternative source of islets, their immaturity and heterogeneity make them inefficiently ameliorate hyperglycemia in rodents. Our previous work showed that NPCCs regress to a transitional-like state immediately after isolation and undergo dynamic transcriptional changes during short-term in vitro culture. The present study aimed to further deline...

Deep‐diving surveys enable observations of new features of behavioural and functional dimensions of the fish that are typically missing from specimen‐based taxonomy. This study documents three rare armoured searobins (Peristediidae: Scalicus engyceros , Paraheminodus murrayi , Peristedion liorhynchus ) in Xianbei Seamount, Zhongsha Islands and Shenhu Canyon in the South China Sea. Not seen in the dead specimen, the fish in lif...

Major depressive disorder (MDD) is a major public health issue worldwide. It not only causes an increased socio-economic burden, but also negatively affects personal lives. It has been shown that depression leads to impairments in synaptic plasticity, such as impaired long-term potentiation (LTP) in the prefrontal cortex (PFC). A recent study reported that administration of agomelatine, a melatonin receptor agonist and 5-hydro...

Assessing the physiological costs of sociality remains challenging due to complex interactions between environmental and social factors. To overcome this challenge, we integrated game theory with empirical research to examine how interspecific competition affects energy expenditure in the cooperatively breeding Asian burying beetle Nicrophorus nepalensis . Our nested tug‐of‐war model made two predictions: beetles facing inters...