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Multiprotein-based nanomedicines with dual CD44/CD133 targeting and GSH-responsive drug release for improving cancer chemotherapyNARA Subscribed
Albumin, a highly biocompatible protein, has been utilized in the construction of anti-cancer drugs for the treatment of various cancers. However, albumin-based nanomedicines still face several clinical challenges, including low stability in the bloodstream, non-specific targeting ability, and lack of controlled release capability. To address these limitations, we developed a multiprotein-based nanomedicine for targeted chemot...
Vibrio infections cause enteritis in grouper fish, leading to high mortality and stunted growth, which is a major challenge for aquaculture. Oligochitosans, marine prebiotics with bioactive properties, have proven their potential for growth promotion and immune regulation. However, the impacts of Vibrio harveyi on the gut microbiome of grouper fish and the potential of oligochitosans to modulate these effects remain poorly und...