NOD‐like receptors (NLRs) serve as crucial innate immune sensors in multicellular organisms, recognizing diverse pathogen‐associated components and regulating immune responses such as nuclear factor kappa B (NF‐κB) signalling and inflammatory pathways. To elucidate the roles of NLRC3 , NLRC5 and NLRX1 in the innate immunity of the Mastacembelus armatus , this study first characterized these genes and examined their response to...