Precipitation concentration is a key climatic factor in the hydrologic system. The purpose of this study was to explore the spatiotemporal variation in precipitation concentration and its possible relationship with large‐scale atmospheric circulation and land use types. Based on daily precipitation recorded at 254 stations during 1961–2019 throughout the Haihe River basin (HRB), linear slope and Manner–Kendall trend analysis w...

Growing evidence reveals that microorganisms in the gut are linked to metabolic health and disease risk in human beings to a considerable extent. The focus of research at this stage must tend to focus on cause-and-effect studies. In addition to being a component of DNA and RNA, purine metabolites can be involved in purine signalling in the body as chemical messengers. Abnormalities in purinergic signalling may lead to neuropat...

Diabetic neuropathic pain (DNP) is frequent among patients with diabetes. We previously showed that P2X3 upregulation in dorsal root ganglia (DRG) plays a role in streptozotocin (STZ)-induced DNP but the underlying mechanism is unclear. Here, a rat model of DNP was established by a single injection of STZ (65 mg/kg). Fasting blood glucose was significantly elevated from the 1 st to 3 rd week. Paw withdrawal thresholds (PWTs) a...