The TRacing Etiology of Non-communicable Diseases (TREND) cohort is a prospective longitudinal cohort and biobank that is mainly based in Ma’anshan, Anhui Province, China. The primary aim of the study is to decipher comprehensive molecular characterization and deep phenotyping for a broad spectrum of chronic non-communicable diseases (NCDs), which focuses on providing mechanistic insights with diagnostic, prognostic and therap...

Background Obesity is associated with a wide variety of metabolic disorders that impose significant burdens on patients and society. The “browning” phenomenon in white adipose tissue (WAT) has emerged as a promising therapeutic strategy to combat metabolic disturbances. However, though the anti-diabetic drug dapagliflozin (DAPA) is thought to promote “browning,” the specific mechanism of this was previously unclear. Methods In...

As the largest producer and consumer of copper, China is facing enormous challenges from carbon peaking and neutrality. This article adopts “bottom‐up” and “top‐down” methods to construct a more accurate model, to predict the CO 2 emissions of China's copper smelting industry, and explores its potential for carbon reduction in the future from three scenarios as the baseline scenario (BAU), the general low‐carbon (NLC), and the...

The large yellow croaker, an endemic migratory species in China’s coastal waters, holds considerable economic importance. It is very necessary and significant to study the spatio-temporal evolution of large yellow croaker fishery based on environmental factors. In this paper, the HY-1C/D Coastal Zone Imager was applied to reveal distributional details of suspended sediment concentration and chlorophyll-a concentration in large...