White spot syndrome virus (WSSV) remains a persistent and significant threat to the global shrimp aquaculture industry. However, its pathogenic mechanisms remain incompletely understood, and no effective intervention strategies are currently available. In this study, we investigated the functional role of VP53B, an envelope structural protein of WSSV, using a combination of infection bioassays, protein structure prediction, pr...

As the world's population grows, aquaculture is becoming a rapidly growing source of protein. Grass carp ( Ctenopharyngodon idella ) is one of the most important aquacultured species in China and has emerged as a significant commercial fish worldwide. However, grass carp reovirus (GCRV) poses a significant threat to grass carp aquaculture. This review covers GCRV biology, phylogeny, pathogenesis, immune response pathways, ther...