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BACKGROUND : Flap transplantation plays a vital role in wound reconstruction. However, the mechanisms by which remote ischemic preconditioning (RIPC) may improve flap survival remain incompletely understood. METHODS : Rats were randomly assigned to three groups: sham, ischemia/reperfusion (I/R), and RIPC + I/R. The I/R model was established by ligating the iliopsoas and thoracodorsal arteries to induce flap ischemia, followed...