Singapore grouper iridovirus (SGIV) is a major viral pathogen threatening grouper aquaculture. The lack of specific antiviral drugs underscores the urgent need to develop safe and effective control strategies. This study demonstrates that tannic acid (TA) exhibits significant anti‐SGIV activity in vitro. In grouper spleen (GS) cells, TA inhibited SGIV replication in a concentration‐dependent manner. Time‐of‐addition assays con...

Singapore grouper iridovirus (SGIV) is a highly pathogenic virus that causes substantial economic losses in marine grouper aquaculture, and effective antiviral agents are currently lacking. In this study, the anti‐SGIV activity of epigallocatechin gallate (EGCG), a natural compound from green tea, was evaluated and its underlying mechanisms were investigated. Cytotoxicity assays showed that EGCG at concentrations up to 12.5 μg...

The cover image is based on the article Elucidating the Immunological Basis of Large Yellow Croaker Larimichthys crocea Offers New Strategies for Its Disease Management by Yinnan Mu et al., https://doi.org/10.1111/raq.70164 . image

Large yellow croaker Larimichthys crocea is a major mariculture species in China, achieving an annual yield of 292,615 tons by 2024. Commercial production faces considerable challenges from disease outbreaks, necessitating comprehensive immune mechanism research. Through comprehensive genomic and transcriptomic investigations, scientists have identified distinguishing characteristics within the L. crocea immune system, encompa...