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Ensuring reproducibility in scientific research is crucial for validating findings, advancing knowledge, and fostering trust within the scientific community. Containerization of code is a widespread practice to help ensure reproducibility in neuroimaging research. However, there exists no universal method of sharing containers, nor is it feasible to broadly enforce rules due to the diversity of research practices. We posit tha...
Ocean Heat Content Sets Another Record in 2025NARA Subscribed
Global ocean warming continued unabated in 2025 in response to increased greenhouse gas concentrations and recent reductions in sulfate aerosols, reflecting the long-term accumulation of heat within the climate system, with conditions evolving toward La Niña during the year. In 2025, global upper 2000 m ocean heat content (OHC) increased by ∼23 ± 8 ZJ relative to 2024 according to IAP/CAS estimates. CIGAR-RT, and Copernicus Ma...
Background Cancer survivors are more susceptible to contracting COVID-19. However, beyond race, age, and sex, less is known about other neighborhood and psychosocial factors contribute to this increased risk. Objective The goal of this study was to examine the associations of individual and area-level social determinants of health (SDOH) measures, medical, lifestyle, and psychosocial factors and COVID-19 infection in a statewi...
Record High Temperatures in the Ocean in 2024NARA Subscribed
Heating in the ocean has continued in 2024 in response to increased greenhouse gas concentrations in the atmosphere, despite the transition from an El Niño to neutral conditions. In 2024, both global sea surface temperature (SST) and upper 2000 m ocean heat content (OHC) reached unprecedented highs in the historical record. The 0–2000 m OHC in 2024 exceeded that of 2023 by 16 ± 8 ZJ (1 Zetta Joules = 10 21 Joules, with a 95% c...
Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory declineNARA Subscribed
Longitudinal investigation of the Apolipoprotein E (APOE) genotype’s impact on Alzheimer’s disease (AD) biomarker progression, focusing on amyloid beta (Aβ) accumulation and gray matter (GM) atrophy, integrating cognitive decline and baseline levels. Longitudinal florbetapir-PET and T1-weighted MRI data from 100 cognitively normal (CN) and mild cognitive impaired (MCI) participants both with considerable global Aβ accumulation...
Critical assessment of missense variant effect predictors on disease-relevant variant dataNARA Subscribed
Regular, systematic, and independent assessments of computational tools that are used to predict the pathogenicity of missense variants are necessary to evaluate their clinical and research utility and guide future improvements. The Critical Assessment of Genome Interpretation (CAGI) conducts the ongoing Annotate-All-Missense (Missense Marathon) challenge, in which missense variant effect predictors (also called variant impact...