Genetic diversity is vital for population survival, yet there is a paucity of studies focusing on the effectiveness of establishing protected areas for maintaining the population genetic diversity of threatened plant species. To evaluate the effectiveness of in situ conservation measures, we used simple sequence repeats (SSR) and single nucleotide polymorphisms (SNP) markers to monitor temporal dynamics in genetic diversity of...

Precipitation fluctuations strongly influence biomass production and its stability of terrestrial ecosystems. However, our understanding of the extent to which plant communities adjust their water‐use strategies in response to non‐growing season precipitation variations remains limited. Our 5‐year snow manipulation experiment in a semi‐arid grassland, complemented with paired stable isotope measurements of δ 18 O and δ 13 C fo...

Iberdomide is a BCS III CELMoD™ agent currently under development for treatment of multiple myeloma. Five formulations were used during clinical development, starting with active ingredient in gelatin capsule (AIC), followed by subsequent formulations in gelatin (F1), HPMC capsules (F2 and F3), and finally the intended commercial form (ICF). A food effect study with the Phase I AIC formulation showed no food effect and two rel...

The effect of dietary retinoic acid (RA) on the growth, lipid deposition, oxidation resistance, immunity, hepatopancreatic and intestinal health of Macrobrachium rosenbergii was evaluated. A total of 1200 prawns (0.22 ± 0.00 g) were divided into six groups and fed their corresponding feed containing 4, 132, 296, 562, 1206 or 2562 mg/kg dietary RA. The weight gain rate, specific growth rate and final body weight of the prawns c...