Drug repositioning is a promising strategy for accelerating drug development and reducing costs by identifying potential indications for existing drugs. Recently, technological advancements have enabled the development of numerous graph convolutional network (GCN)-based methods for drug repositioning. However, many existing methods overlook the distinct roles of nodes within drug-disease association graphs, limiting their abil...

The intensification of mariculture has increased nitrogen and phosphorus pollution in aquaculture wastewater. Conventional treatments often prove inefficient under saline conditions. To address this challenge, we developed an innovative aerobic denitrification reactor using Pseudomonas chloritidismutans K14, specifically tailored for seawater systems. Our study examined the effects of hydraulic retention time (HRT) and carbon-...