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European Journal of Clinical Pharmacology · 2024 · Vol. 80 · Issue 1 · Springer
Purpose This study intends to assess the reference range of lamotrigine concentration for treating childhood epilepsy. Methods PubMed, Ovid-Embase, The Cochrane Library, CNKI, WanFang data and VIP databases were searched from database inception to January 2022. RCT, cohort study, case–control study, cross-sectional study that estimated the reference range of lamotrigine for children epilepsy treatment were included. The data e...
European Journal of Clinical Pharmacology · 2020 · Vol. 76 · Issue 12 · Springer
Purpose To evaluate the toxicity of azithromycin in neonates, infants, and children. Methods A systematic review was performed for relevant studies using Medline (Ovid), PubMed, Cochrane Central Register of Controlled Trials, EMBASE, CINAHL, and International Pharmaceutical Abstracts. We calculated the pooled incidence of adverse drug reactions (ADRs) associated with azithromycin based on prospective studies (RCTs and prospect...