Mycophenolic acid (MPA), the active moiety of both mycophenolate mofetil (MMF) and enteric-coated mycophenolate sodium (EC-MPS), serves as a primary immunosuppressant for maintaining solid organ transplants. Therapeutic drug monitoring (TDM) enhances treatment outcomes through tailored approaches. This study aimed to develop an evidence-based guideline for MPA TDM, facilitating its rational application in clinical settings. Th...

Freeze–thaw‐induced N 2 O pulses could account for nearly half of annual N 2 O fluxes in cold climates, but their episodic nature, sensitivity to snow cover dynamics, and the challenges of cold‐season monitoring complicate their accurate estimation and representation in global models. To address these challenges, we combined in situ automated high‐frequency flux measurements with cross‐ecoregion soil core incubations to invest...

The efficient coverage of underwater wireless sensor networks (UWSNs) has become increasingly important because of the scarcity of underwater node resources. Complex underwater environments, water flow forces, and undulating seabed reduce the coverage effect of underwater nodes, even leading to coverage holes in UWSNs. To solve the problems of uneven coverage distribution and coverage holes, a three-dimensional iterative enhan...