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NARA Subscribed2
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Springer Nature2
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Inflammation Research2
Publication Year
20241
20231
Linmiao Lie results 2 · Newest (Page 1/1, per page 25)
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Author: Linmiao Lie ×Clear All Filters
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Viperin inhibits interferon-γ production to promote Mycobacterium tuberculosis survival by disrupting TBK1-IKKε-IRF3-axis and JAK-STAT signalingNARA Subscribed
Inflammation Research · 2024 · Vol. 73 · Issue 6 · Springer
Yao Liang; Yun Liang; Qi Wang; Qianna Li; Yingqi Huang; Rong Li; Xiaoxin Pan; Linmiao Lie; Hui Xu; Zhenyu Han; Honglin Liu; Qian Wen; Chaoying Zhou; Li Ma; Xinying Zhou
Objectives and design As an interferon-inducible protein, Viperin has broad-spectrum antiviral effects and regulation of host immune responses. We aim to investigate how Viperin regulates interferon-γ (IFN-γ) production in macrophages to control Mycobacterium tuberculosis (Mtb) infection. Methods We use Viperin deficient bone-marrow-derived macrophage (BMDM) to investigate the effects and machines of Viperin on Mtb infection....
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Viperin deficiency promotes dendritic cell activation and function via NF-kappaB activation during Mycobacterium tuberculosis infectionNARA Subscribed
Inflammation Research · 2023 · Vol. 72 · Issue 1 · Springer
Xinying Zhou; Hui Xu; Qianna Li; Qi Wang; Honglin Liu; Yingqi Huang; Yao Liang; Linmiao Lie; Zhenyu Han; Yaoxin Chen; Yulan Huang; Wenle Zhou; Qian Wen; Chaoying Zhou; Shengfeng Hu; Li Ma
Objectives and design Dendritic cells (DCs) are one of the key immune cells in bridging innate and adaptive immune response against Mycobacterium tuberculosis (Mtb) infection. Interferons (IFNs) play important roles in regulating DC activation and function. Virus-inhibitory protein, endoplasmic reticulum-associated, interferon-inducible (Viperin) is one of the important IFN-stimulated genes (ISGs), and elicits host defense aga...
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