Background There is lack of research on corticosteroid use for severe and critical COVID-19 patients with Omicron variant infection. Methods This multi-center retrospective cohort study involved 1167 patients from 59 ICUs across the mainland of China diagnosed with severe or critical SARS-CoV-2 Omicron variant infection between November 1, 2022, and February 11, 2023. Patients were segregated into two groups based on their cor...