Lisa Ferguson results 17
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SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
Perspectives of an NCI T32 Training Program Designed to Train a Diverse Workforce in Cancer Health Equity ResearchNARA Subscribed
With cancer health disparities on the rise in the United States (USA), there is an increased need for novel approaches to address these challenges. One such approach that may help address these disparities is increasing diversity in the biomedical research workforce. The Cancer Health Equity and Career Development Program (CHECDP) embodies this approach by recruiting and training underrepresented minorities in cancer research...
Purpose of Review Environmental chemical exposures may disrupt child development, with long-lasting health impacts. To date, U.S. studies of early environmental exposures have been limited in size and diversity, hindering power and generalizability. With harmonized data from over 60,000 participants representing 69 pregnancy cohorts, the National Institutes of Health’s Environmental influences on Child Health Outcomes (ECHO) P...
The rapid rate of climate change in the Arctic is causing broad-scale changes to the physical environment and biological communities. Characterizing the foraging ecology and habitat use of Arctic marine top predators of high ecological and cultural significance is essential to our understanding of their vulnerability to ecosystem change, especially when there is potential for dietary resource competition in spatially co-occurr...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Estimating narwhal ( Monodon monoceros ) age using tooth layers and aspartic acid racemization of eye lens nucleiNARA Subscribed
Counting growth‐layer groups (GLGs) in teeth is one of the most precise and widely accepted methods for aging marine mammals. Male narwhals have a large erupted tusk that can be used for aging, but this tusk is often difficult or expensive to obtain from hunters and most females do not display the tusk; thus, alternative methods for narwhal aging are needed. In this study, we aged narwhals by counting annual GLGs in embedded t...
Reconstruction of the demographic and evolutionary history of populations assuming a consensus tree‐like relationship can mask more complex scenarios, which are prevalent in nature. An emerging genomic toolset, which has been most comprehensively harnessed in the reconstruction of human evolutionary history, enables molecular ecologists to elucidate complex population histories. Killer whales have limited extrinsic barriers to...
Use of mass spectrometry to measure aspartic acid racemization for ageing beluga whalesNARA Subscribed
We developed a novel analytical method to measure the D‐ and L‐isomers of aspartic acid ( AA ) in the eye lens of beluga whales ( Delphinapterus leucas ) for age determination. The method was based on hydrolysis of the eye lens under acidic conditions followed by direct injection onto a Chirobiotic T (25 cm × 4.6 ID , 5 μm particle size) high performance liquid chromatography analytical column and detection by tandem mass spec...
Determination of Quantitative Trait Loci (QTL) for Early Maturation in Rainbow Trout (Oncorhynchus mykiss)NARA Subscribed
To identify quantitative trait loci (QTL) influencing early maturation (EM) in rainbow trout ( Oncorhynchus mykiss ), a genome scan was performed using 100 microsatellite loci across 29 linkage groups. Six inter-strain paternal half-sib families using three inter-strain F 1 brothers (approximately 50 progeny in each family) derived from two strains that differ in the propensity for EM were used in the study. Alleles derived fr...
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