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Springer Nature1
Journal
Molecular Neurobiology1
Publication Year
20211
Lisa Lott results 1 · Newest (Page 1/1, per page 25)
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High Genetic Addiction Risk Score (GARS) in Chronically Prescribed Severe Chronic Opioid Probands Attending Multi-pain Clinics: an Open Clinical Pilot TrialNARA Subscribed
Molecular Neurobiology · 2021 · Vol. 58 · Issue 7 · Springer
Mark Moran; Kenneth Blum; Jessica Valdez Ponce; Lisa Lott; Marjorie C. Gondré–Lewis; Sampada Badgaiyan; Raymond Brewer; B. William Downs; Philip Fynman; Alexander Weingarten; Jean Lud Cadet; David E. Smith; David Baron; Panayotis K. Thanos; Edward J. Modestino; Rajendra D. Badgaiyan; Igor Elman; Mark S. Gold
Millions of Americans experience pain daily. In 2017, opioid overdose claimed 64,000 lives increasing to 84,000 lives in 2020, resulting in a decrease in national life expectancy. Chronic opioid use results in dependency, drug tolerance, neuroadaptation, hyperalgesia, potential addictive behaviors, or Reward Deficiency Syndrome (RDS) caused by a hypodopaminergia. Evaluation of pain clinic patients with the Genetic Addiction Ri...
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